Mosquito-borne diseases are a serious threat to public health and account for more than 100 million infections annually worldwide. Many of these diseases (e.g., dengue and chikungunya) are endemic to the tropics, including Singapore, and have persisted despite long-term efforts to reduce transmission. Most ongoing research on insect-borne disease transmission predominantly focuses on its molecular basis and proximate mechanisms, but little is known about the movement of mosquitoes within a city, and how that could contribute to disease transmission as well as the implications for disease control and management. In our lab, we first conduct an island wide sampling and employ both morphological and molecular methods in estimating species richness, diversity and abundance across diverse ecological niches: Urban, parks, mangrove, forests. Next, we investigate the role that adult reproduction plays in disease transmission, especially in local dengue vectors such as Aedes aegypti, A. albopictus and A. malayensis using both geometric morphometric and population genomic tools.